The Argentine was not aware of Uruguay on Sunday night, at the Monumental de Nuñez stadium, in Buenos Aires.
In the derby valid for the fifth round of the World Cup qualifiers (the game had been postponed), the hosts scored 3-0 on the scoreboard.
The visitors even started better, they even sent a ball to the crossbar with Suarez. But, at 37, a cross from Messi ended up not hitting anyone and dying in the net.
Five minutes later, De Paul widened by taking advantage of a bounce inside the area.
The goals brought down the Uruguayans, who could no longer react. Calm, sovereign, Argentina still scored with Lautaro, after a cross from De Paul.
In the final minutes, Muslera still prevented two more goals from the Argentines and avoided humiliation.
The result left Argentina with 22 points, behind only Brazil, who have 28 points, after 10 games played.
Uruguay, with 16 points, occupies the fourth place, at least for now, but already with 11 games played.
Next Thursday, Argentina will host Peru again at the Monumental de Nuñez. Uruguay will visit Brazil, on the same day, at Arena Amazônia.
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