They manage to transplant two genetically modified pig kidneys into a human

New milestone in science and medicine. A team of US researchers has managed to successfully transplant two genetically modified pig kidneys into a human who was brain dead.

Those in charge of this xenotransplantation in the clinical trial phase are researchers at the Heersink School of Medicine, University of Alabama at Birmingham, United States, and the results have been published today in an article in the American Journal of Transplantation.

The study recipient was transplanted with two modified pig kidneys genetically in the abdomen after his native kidneys were removed. The organs were obtained from a genetically modified pig in a pathogen-free facility.

Transplanted kidneys filtered blood, produced urine and, what is more important, they were not rejected immediately. The kidneys they remained viable until the end of the study, 77 hours after transplantation. Thus, this process demonstrated the long-term viability of the procedure and how such a transplant might work in the real world.

The peer-reviewed research was conducted to meet standards directly comparable to those that would apply to a phase I human clinical trial, mirroring every step of a standard human-to-human transplant, the researchers explain. included the Institutional Review Board and Institutional Animal Care and Use Committee approval, confirmation of tissue compatibility prior to commencing operations, use of standard human-to-human transplantation procedures to remove, preserve, transport, and transplant kidneys into a human, and administration of standard immunosuppressive therapy to the receiver.

The transplant recipient is Jim Parsons, 57, and a registered organ donor. What your organs were not suitable for donation his family allowed the UAB to keep him connected to a respirator so that his body would continue to function during the study. “Mr. Parsons and his family allowed us to precisely replicate how we would perform this transplant in a living human being. Your powerful contribution will save thousands of lives, and that could start in the very near future,” admits Locke, who explains that it has been proposed that it be known as “The Parsons Model.”