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Scientists have discovered a way to deprive cancer cells of “fuel” with the help of cold

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THIS MESSAGE (MATERIAL) IS CREATED AND (OR) DISTRIBUTED BY A FOREIGN MASS MEDIA PERFORMING THE FUNCTIONS OF A FOREIGN AGENT AND (OR) A RUSSIAN LEGAL ENTITY PERFORMING THE FUNCTIONS OF A FOREIGN AGENT.

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Scientists at the Karolinska Institute in Sweden, who are studying the behavior of a certain type of fat in response to cold, have made a discovery that is significant for cancer treatment. It is reported by “Hitech” with reference to the journal Nature.

Researchers have reportedly learned more about how the body metabolizes glucose. Presumably, low temperatures can deprive tumor cells of a vital source of “fuel” that they need to live.

The scientists focused on so-called brown adipose tissue, one of two types of adipose tissue in mammals. Brown fat is well developed in newborns and in hibernating animals. In an adult, it is present and metabolically active, but regresses with age.

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Unlike regular white fat, which stores additional energy in the form of lipids, brown fat readily burns energy to keep the body warm in colder temperatures.

The scientists tried to find out how the activation of brown fat can affect the growth of a tumor whose growth can be provoked by glucose. During the experiment, they used mouse models with various types of cancer. The rodents were exposed to both cold and warm temperatures. Mice kept at 4°C had much slower tumor growth and lived almost twice as long as mice kept at 30°C.

It is noted that the analysis of tissues, cellular reactions and glucose metabolism showed that lower temperatures led to active absorption of glucose by brown adipose tissue, and they were not detected in tumor cells.

Source: Rosbalt

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