While we’re used to the idea that teeth only grow twice, a new drug may make it possible to grow a third set. Scientists are making significant progress in developing a breakthrough drug that could potentially enable tooth regrowth.
Can teeth grow back? Scientists are developing a new, groundbreaking drug
While we may have outgrown the tooth fairy tale, it seems that the possibility of growing teeth is becoming a reality again. A group of Japanese researchers and dentists from the Kitano Hospital Medical Research Institute in Osaka made an extraordinary discovery that will enable tooth regrowth in humans. They are developing an “antibody drug that regenerates teeth.” The basis is the research results of Dr. Katsu Takahashi from Oral and Maxillofacial Surgery at Kyoto University. – The idea of growing new teeth is every dentist’s dream. I’ve been working on this since college – he told a Japanese newspaper
The world’s first drug for tooth regrowth. It is undergoing clinical trials in Japan
The breakthrough came in 2007, when a mouse with extra teeth was discovered. The cause of the extra teeth was found to be a deficiency of the USAG-1 gene. Based on the research results, scientists concluded that in people with congenital or acquired dental defects, teeth can be regenerated by inactivating the USAG-1 protein using a drug. To test this hypothesis, they used anti-USAG-1 antibodies. The tooth regrowth medicine is intended for people who, due to congenital factors, are missing a full set of adult teeth.
What can you do at the dentist under the National Health Fund? (illustrative photo) Photo Grzegorz Celejewski / Agencja Wyborcza.pl
Research on tooth regeneration published in the journal “” shows:
One systemic administration of a neutralizing antibody can generate an entire tooth.
Clinical trials are scheduled to begin in July 2024. A team of researchers from Japan aims to have the drug ready for general use by 2030. Currently, people suffering from dental diseases have no other treatment option than implants. If successful, this study will introduce a new alternative and treatment option. If you feel like it, vote in our poll below.
Source: Gazeta
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