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Moderna and Sputnik Vaccines outperform Pfizer in Hungarian study

The COVID-19 vaccines from Moderna Inc. and Russia’s Sputnik V both outperformed Pfizer Inc. and BioNTech SE’s version in terms of efficacy in a large-scale study of five different vaccines conducted by Hungarian researchers.

Moderna’s vaccine was 88.7% effective in protecting against coronavirus infection and 93.6% effective against COVID-related mortality, compared to 85.7% and 95.4%, respectively, for Sputnik, according to the study published Wednesday on the website of the medical journal Clinical Microbiology and Infection. Pfizer ranked third with 83.3% and 90.6%, respectively.

The research reviewed the effectiveness of five vaccines in people at least seven days after receiving their second dose. Data on more than 3.7 million vaccinated people aged 16 and over from January to June of this year were reviewed.

The wide range of vaccines available in Hungary enables the evaluation of vaccine efficacy in a real world setting in a Central European country and places Hungary in the unique position of providing detailed information on multiple types of vaccines from the same country.”The authors, including Hungarian Human Resources Minister Miklos Kasler, and Medical Director Cecilia Muller, wrote in the study.

Pfizer was administered more frequently, to 1.5 million people, followed by the Chinese Sinopharm with 895,465, the Russian Sputnik V with 820,560, AstraZeneca with 304,138 and Modern with 222,892, according to the study. Pfizer and Sinopharm of China had the highest proportion of vaccines given to people aged 65 and over, while Sputnik had the lowest proportion, the data showed.

AstraZeneca was 71.5% effective against infection and 74.5% against COVID-related death, while Sinopharm was 68.7% effective against infection and 87.8% against death.

So much AstraZeneca What Sinopharm were less than 50% effective against COVID infection in people 85 and older, according to the study. That compared to 90.9% for the same age group for Sputnik, 84.1% for Moderna and 74.3% for Pfizer.

Hungary had one of the highest per capita COVID-related death rates in the world earlier this year. The country, whose vaccination rates are below the average for Western Europe, reported a record number of daily infections on Wednesday as the fourth wave of the virus continues to spread.


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