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Researchers believe they have found a cure for baldness

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It is one of the aesthetic problems that most affects men. Although science has presented some solutions, it has not been able to reverse the cause. Now, a recent study seems to have found the cure for baldness.

As published in the Biophysical JournalScientists discovered that a single chemical is key to controlling when hair follicle cells divide and when they die.

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The researchers further found that this breakthrough could not only lead to an effective treatment of baldness, but ultimately speed up wound healing because the follicles are a source of stem cells.

In the human body, most cells have a specific form and function determined during embryonic development that does not change. A blood cell, for example, cannot become a nerve cell, or vice versa. However, stem cells can develop into other types of cells.

A) Yes, Stem cells’ adaptability makes them valuable for repairing damaged tissues or organs.

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Qixuan Wang, a mathematical biologist at the University of California, Riverside, and a co-author of the study, said: “In science fiction, when characters heal quickly from injuries, the idea is that the stem cells allowed it.”

“In real life, our new research brings us closer to understanding stem cell behavior, so we can control it and promote wound healing.” Wang added.

In response to injuries, the liver and stomach regenerate. However, Wang’s team of researchers studied hair follicles because they are the only human organ that automatically and periodically regenerates, even without injury.

Scientists discovered how TGF-beta, a type of protein, controls the process by which hair follicle cells, including stem cells, divide and form new cells, or orchestrate their own death, eventually leading to the death of the entire hair follicle.

“TGF-beta has two opposing roles. It helps activate some hair follicle cells to produce new life, and later helps orchestrate apoptosis, the process of cell death,” Wang explained.

As with many chemicals, it is the amount that makes the difference in the result. If the cell produces a certain amount of TGF-beta, it activates cell division. However, too much causes apoptosis, that is, cell death.

And while no one is entirely sure why hair follicles die, some hypotheses suggest it’s a trait inherited from animals that shed hair to survive hot summer temperatures or try to camouflage.

Even when a hair follicle kills itself, it never kills its reservoir of stem cells. When the surviving stem cells receive the signal to regenerate, they divide, create new cells, and develop into a new follicle,” Wang explained.

If researchers can pinpoint how TGF-beta activates cell division and how the chemical communicates with other important genes, it may be possible to activate follicle stem cells and stimulate hair growth. (YO)

Source: Eluniverso

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