Using frozen sperm in in vitro fertilization achieves the same results as fresh semen, according to a study carried out on 7,969 couples by researchers from the Eugin Group.
The research, published by the journal ‘Human Reproduction’is the largest sample analyzed in a scientific study of this type to date and has taken into account two novel factors: control of both the male and female factor and the use of the ICSI technique, with which an ovum is directly inseminated with a single sperm.
The research, published in the prestigious scientific journal ‘Human Reproduction’, wanted to find out the effect of slow freezing cryopreservation on reproductive outcomes.
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As explained by the researcher Marc Torra-Massanamost studies that compare reproductive results between fresh and cryopreserved semen include male patients with severe pathologies, such as decreased motile sperm in a semen sample, or women of advanced maternal age, where altered gamete quality may partially mask the full effect of freezing/thawing.
However, in this research they have only selected patients with normal semen samples and cycles with fresh oocytes from a good quality donor to control both the female and male factors.
“Although slow-freezing sperm cryopreservation is common practice, the use of frozen-thawed semen often has reduced motility and vitality. However, its use for ICSI, a technique in which an ovum is inseminated by microinjection of a single previously selected sperm, is considered adequate in terms of reproductive results.” has detailed Torra-Massana.
“Thanks to the large sample, and the incorporation of these two factors in the research -he added-, we have managed to conclude that sperm cryopreservation has a clinically irrelevant impact after using the ICSI technique in in vitro fertilization processes, both in the fertilization rate as in the rate of babies born”, he pointed.
SOURCE: EFE AGENCY.
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Source: Gestion
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